pentobarbital will lessen the level or influence of buprenorphine buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.pentobarbital and olopatadine intranasal both maximize sedation. Steer clear of or Use Alternate Drug. Coadministration improves risk of CNS melancholy, which may lead to additive impairment of psych